CTSS Back

cathepsin S

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NCBI Description of CTSS
The protein encoded by this gene, a member of the peptidase C1 family, is a lysosomal cysteine proteinase that may participate in the degradation of antigenic proteins to peptides for presentation on MHC class II molecules. The encoded protein can function as an elastase over a broad pH range in alveolar macrophages. Alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.

Community Annotation of CTSS Add / Edit CTSS: Annotations

No community annotations yet for CTSS.
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Figure notes


• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


Legend

CTSS is highly significantly mutated in
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CTSS is significantly mutated in
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CTSS is near significance in
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Click on a tumor type to see its full list of significant genes.

Data details


• Mutation list for CTSS