CTPS Back

CTP synthase

External References:      Wikipedia GeneCards HUGO COSMIC Google Scholar

NCBI Description of CTPS
The catalytic conversion of UTP to CTP is accomplished by the enzyme cytidine-5-prime-triphosphate synthetase. The enzyme is important in the biosynthesis of phospholipids and nucleic acids, and plays a key role in cell growth, development, and tumorigenesis. The region to which the CTPS gene has been mapped is the location of breakpoints involved in several tumor types

Community Annotation of CTPS Add / Edit CTPS: Annotations

No community annotations yet for CTPS.
Sort mutations by: Tumor type  Mutation type  Position  
Straightedge cursor Expand

Figure notes


• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


Legend

CTPS is highly significantly mutated in
(none)
CTPS is significantly mutated in
(none)
CTPS is near significance in
(none)

Click on a tumor type to see its full list of significant genes.

Data details


• Mutation list for CTPS