collagen triple helix repeat containing 1

External References:      Wikipedia GeneCards HUGO COSMIC Google Scholar

NCBI Description of CTHRC1

This locus encodes a protein that may play a role in the cellular response to arterial injury through involvement in vascular remodeling. Mutations at this locus have been associated with Barrett esophagus and esophageal adenocarcinoma. Alternatively spliced transcript variants have been described.

Community Annotation of CTHRC1 Add / Edit CTHRC1: Annotations

No community annotations yet for CTHRC1.
Sort mutations by: Tumor type  Mutation type  Position  
Straightedge cursor Expand

Figure notes

• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


CTHRC1 is highly significantly mutated in
CTHRC1 is significantly mutated in
CTHRC1 is near significance in

Click on a tumor type to see its full list of significant genes.

Data details

Mutation list for CTHRC1