connective tissue growth factor

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NCBI Description of CTGF

The protein encoded by this gene is a mitogen that is secreted by vascular endothelial cells. The encoded protein plays a role in chondrocyte proliferation and differentiation, cell adhesion in many cell types, and is related to platelet-derived growth factor. Certain polymorphisms in this gene have been linked with a higher incidence of systemic sclerosis.

Community Annotation of CTGF Add / Edit CTGF: Annotations

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Figure notes

• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


CTGF is highly significantly mutated in
CTGF is significantly mutated in
CTGF is near significance in

Click on a tumor type to see its full list of significant genes.

Data details

Mutation list for CTGF