CTBP1 Back

C-terminal binding protein 1

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NCBI Description of CTBP1
This gene encodes a protein that binds to the C-terminus of adenovirus E1A proteins. This phosphoprotein is a transcriptional repressor and may play a role during cellular proliferation. This protein and the product of a second closely related gene, CTBP2, can dimerize. Both proteins can also interact with a polycomb group protein complex which participates in regulation of gene expression during development. Alternative splicing of transcripts from this gene results in multiple transcript variants.

Community Annotation of CTBP1 Add / Edit CTBP1: Annotations

No community annotations yet for CTBP1.
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Figure notes


• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


Legend

CTBP1 is highly significantly mutated in
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CTBP1 is significantly mutated in
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CTBP1 is near significance in
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Click on a tumor type to see its full list of significant genes.

Data details


• Mutation list for CTBP1