CSTF2 Back

cleavage stimulation factor, 3' pre-RNA, subunit 2, 64kDa

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NCBI Description of CSTF2
This gene encodes a nuclear protein with an RRM (RNA recognition motif) domain. The protein is a member of the cleavage stimulation factor (CSTF) complex that is involved in the 3' end cleavage and polyadenylation of pre-mRNAs. Specifically, this protein binds GU-rich elements within the 3'-untranslated region of mRNAs.

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Figure notes


• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


Legend

CSTF2 is highly significantly mutated in
(none)
CSTF2 is significantly mutated in
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CSTF2 is near significance in
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Click on a tumor type to see its full list of significant genes.

Data details


• Mutation list for CSTF2