CSTF1 Back

cleavage stimulation factor, 3' pre-RNA, subunit 1, 50kDa

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NCBI Description of CSTF1

This gene encodes one of three subunits which combine to form cleavage stimulation factor (CSTF). CSTF is involved in the polyadenylation and 3'end cleavage of pre-mRNAs. Similar to mammalian G protein beta subunits, this protein contains transducin-like repeats. Several transcript variants with different 5' UTR, but encoding the same protein, have been found for this gene.

Community Annotation of CSTF1 Add / Edit CSTF1: Annotations

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Figure notes


• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


Legend

CSTF1 is highly significantly mutated in
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CSTF1 is significantly mutated in
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CSTF1 is near significance in
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Click on a tumor type to see its full list of significant genes.

Data details


Mutation list for CSTF1