CSRNP1 Back

cysteine-serine-rich nuclear protein 1

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NCBI Description of CSRNP1
This gene encodes a protein that localizes to the nucleus and expression of this gene is induced in response to elevated levels of axin. The Wnt signalling pathway, which is negatively regulated by axin, is important in axis formation in early development and impaired regulation of this signalling pathway is often involved in tumors. A decreased level of expression of this gene in tumors compared to the level of expression in their corresponding normal tissues suggests that this gene product has a tumor suppressor function. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments.

Community Annotation of CSRNP1 Add / Edit CSRNP1: Annotations

No community annotations yet for CSRNP1.
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Figure notes


• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


Legend

CSRNP1 is highly significantly mutated in
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CSRNP1 is significantly mutated in
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CSRNP1 is near significance in
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Click on a tumor type to see its full list of significant genes.

Data details


• Mutation list for CSRNP1