CSF1 Back

colony stimulating factor 1 (macrophage)

External References:      Wikipedia GeneCards HUGO COSMIC Google Scholar

NCBI Description of CSF1
The protein encoded by this gene is a cytokine that controls the production, differentiation, and function of macrophages. The active form of the protein is found extracellularly as a disulfide-linked homodimer, and is thought to be produced by proteolytic cleavage of membrane-bound precursors. The encoded protein may be involved in development of the placenta. Alternate splicing results in multiple transcript variants.

Community Annotation of CSF1 Add / Edit CSF1: Annotations

No community annotations yet for CSF1.
Sort mutations by: Tumor type  Mutation type  Position  
Straightedge cursor Expand

Figure notes


• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


Legend

CSF1 is highly significantly mutated in
(none)
CSF1 is significantly mutated in
(none)
CSF1 is near significance in
(none)

Click on a tumor type to see its full list of significant genes.

Data details


• Mutation list for CSF1