CRYL1 Back

crystallin, lambda 1

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NCBI Description of CRYL1
The uronate cycle functions as an alternative glucose metabolic pathway, accounting for about 5% of daily glucose catabolism. The product of this gene catalyzes the dehydrogenation of L-gulonate into dehydro-L-gulonate in the uronate cycle. The enzyme requires NAD(H) as a coenzyme, and is inhibited by inorganic phosphate. A similar gene in the rabbit is thought to serve a structural role in the lens of the eye.

Community Annotation of CRYL1 Add / Edit CRYL1: Annotations

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Figure notes


• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


Legend

CRYL1 is highly significantly mutated in
(none)
CRYL1 is significantly mutated in
(none)
CRYL1 is near significance in
(none)

Click on a tumor type to see its full list of significant genes.

Data details


• Mutation list for CRYL1