CRNKL1 Back

crooked neck pre-mRNA splicing factor-like 1 (Drosophila)

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NCBI Description of CRNKL1
The crooked neck (crn) gene of Drosophila is essential for embryogenesis and is thought to be involved in cell cycle progression and pre-mRNA splicing. This gene is similar in sequence to crn and encodes a protein which can localize to pre-mRNA splicing complexes in the nucleus. The encoded protein, which contains many tetratricopeptide repeats, is required for pre-mRNA splicing.

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Figure notes


• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


Legend

CRNKL1 is highly significantly mutated in
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CRNKL1 is significantly mutated in
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CRNKL1 is near significance in
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Click on a tumor type to see its full list of significant genes.

Data details


• Mutation list for CRNKL1