CRHBP Back

corticotropin releasing hormone binding protein

External References:      Wikipedia GeneCards HUGO COSMIC Google Scholar

NCBI Description of CRHBP
Corticotropin-releasing hormone is a potent stimulator of synthesis and secretion of preopiomelanocortin-derived peptides. Although CRH concentrations in the human peripheral circulation are normally low, they increase throughout pregnancy and fall rapidly after parturition. Maternal plasma CRH probably originates from the placenta. Human plasma contains a CRH-binding protein which inactivates CRH and which may prevent inappropriate pituitary-adrenal stimulation in pregnancy.

Community Annotation of CRHBP Add / Edit CRHBP: Annotations

No community annotations yet for CRHBP.
Sort mutations by: Tumor type  Mutation type  Position  
Straightedge cursor Expand

Figure notes


• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


Legend

CRHBP is highly significantly mutated in
(none)
CRHBP is significantly mutated in
(none)
CRHBP is near significance in
(none)

Click on a tumor type to see its full list of significant genes.

Data details


• Mutation list for CRHBP