CR2 Back

complement component (3d/Epstein Barr virus) receptor 2

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NCBI Description of CR2

This gene encodes a membrane protein, which functions as a receptor for Epstein-Barr virus (EBV) binding on B and T lymphocytes. Genetic variations in this gene are associated with susceptibility to systemic lupus erythematosus type 9 (SLEB9). Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

Community Annotation of CR2 Add / Edit CR2: Annotations

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Figure notes


• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


Legend

CR2 is highly significantly mutated in
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CR2 is significantly mutated in
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CR2 is near significance in
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Click on a tumor type to see its full list of significant genes.

Data details


Mutation list for CR2