CPNE2 Back

copine II

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NCBI Description of CPNE2

Calcium-dependent membrane-binding proteins may regulate molecular events at the interface of the cell membrane and cytoplasm. This gene is one of several genes that encode a calcium-dependent protein containing two N-terminal type II C2 domains and an integrin A domain-like sequence in the C-terminus. Sequence analysis identified multiple alternatively spliced transcript variants but their full-length natures could not be determined.

Community Annotation of CPNE2 Add / Edit CPNE2: Annotations

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Figure notes


• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


Legend

CPNE2 is highly significantly mutated in
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CPNE2 is significantly mutated in
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CPNE2 is near significance in
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Click on a tumor type to see its full list of significant genes.

Data details


Mutation list for CPNE2