CPLX2 Back

complexin 2

External References:      Wikipedia GeneCards HUGO COSMIC Google Scholar

NCBI Description of CPLX2

Proteins encoded by the complexin/synaphin gene family are cytosolic proteins that function in synaptic vesicle exocytosis. These proteins bind syntaxin, part of the SNAP receptor. The protein product of this gene binds to the SNAP receptor complex and disrupts it, allowing transmitter release. Two transcript variants encoding the same protein have been found for this gene.

Community Annotation of CPLX2 Add / Edit CPLX2: Annotations

No community annotations yet for CPLX2.
Sort mutations by: Tumor type  Mutation type  Position  
Straightedge cursor Expand

Figure notes

• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


CPLX2 is highly significantly mutated in
CPLX2 is significantly mutated in
CPLX2 is near significance in

Click on a tumor type to see its full list of significant genes.

Data details

Mutation list for CPLX2