CPLX1 Back

complexin 1

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NCBI Description of CPLX1
Proteins encoded by the complexin/synaphin gene family are cytosolic proteins that function in synaptic vesicle exocytosis. These proteins bind syntaxin, part of the SNAP receptor. The protein product of this gene binds to the SNAP receptor complex and disrupts it, allowing transmitter release.

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Figure notes


• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


Legend

CPLX1 is highly significantly mutated in
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CPLX1 is significantly mutated in
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CPLX1 is near significance in
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Click on a tumor type to see its full list of significant genes.

Data details


• Mutation list for CPLX1