CPEB2 Back

cytoplasmic polyadenylation element binding protein 2

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NCBI Description of CPEB2

The protein encoded by this gene is highly similar to cytoplasmic polyadenylation element binding protein (CPEB), an mRNA-binding protein that regulates cytoplasmic polyadenylation of mRNA as a trans factor in oogenesis and spermatogenesis. Studies of the similar gene in mice suggested a possible role of this protein in transcriptionally inactive haploid spermatids. Alternatively spliced transcript variants encoding distinct isoforms have been described.

Community Annotation of CPEB2 Add / Edit CPEB2: Annotations

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Figure notes


• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


Legend

CPEB2 is highly significantly mutated in
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CPEB2 is significantly mutated in
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CPEB2 is near significance in
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Click on a tumor type to see its full list of significant genes.

Data details


Mutation list for CPEB2