COX18 Back

COX18 cytochrome c oxidase assembly homolog (S. cerevisiae)

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NCBI Description of COX18

COX18 encodes a cytochrome c oxidase (COX)-assembly protein. The S. cerevisiae Cox18 protein catalyzes the insertion of the Cox2 (MTCO2; MIM 516040) C-terminal tail into the mitochondrial inner membrane, an intermediate step in the assembly of complex IV of the mitochondrial respiratory chain (Sacconi et al., 2005 [PubMed 16212937]).[supplied by OMIM, Mar 2008].

Community Annotation of COX18 Add / Edit COX18: Annotations

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Figure notes


• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


Legend

COX18 is highly significantly mutated in
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COX18 is significantly mutated in
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COX18 is near significance in
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Click on a tumor type to see its full list of significant genes.

Data details


Mutation list for COX18