coronin, actin binding protein, 1C

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NCBI Description of CORO1C

This gene encodes a member of the WD repeat protein family. WD repeats are minimally conserved regions of approximately 40 amino acids typically bracketed by gly-his and trp-asp (GH-WD), which may facilitate formation of heterotrimeric or multiprotein complexes. Members of this family are involved in a variety of cellular processes, including cell cycle progression, signal transduction, apoptosis, and gene regulation. Three transcript variants encoding two different isoforms have been found for this gene.

Community Annotation of CORO1C Add / Edit CORO1C: Annotations

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Figure notes

• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


CORO1C is highly significantly mutated in
CORO1C is significantly mutated in
CORO1C is near significance in

Click on a tumor type to see its full list of significant genes.

Data details

Mutation list for CORO1C