COPS3 Back

COP9 constitutive photomorphogenic homolog subunit 3 (Arabidopsis)

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NCBI Description of COPS3
The protein encoded by this gene possesses kinase activity that phosphorylates regulators involved in signal transduction. It phosphorylates I kappa-Balpha, p105, and c-Jun. It acts as a docking site for complex-mediated phosphorylation. The gene is located within the Smith-Magenis syndrome region on chromosome 17. Two transcript variants encoding different isoforms have been found for this gene.

Community Annotation of COPS3 Add / Edit COPS3: Annotations

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Figure notes


• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


Legend

COPS3 is highly significantly mutated in
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COPS3 is significantly mutated in
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COPS3 is near significance in
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Click on a tumor type to see its full list of significant genes.

Data details


• Mutation list for COPS3