COPB1 Back

coatomer protein complex, subunit beta 1

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NCBI Description of COPB1

This gene encodes a protein subunit of the coatomer complex associated with non-clathrin coated vesicles. The coatomer complex, also known as the coat protein complex 1, forms in the cytoplasm and is recruited to the Golgi by activated guanosine triphosphatases. Once at the Golgi membrane, the coatomer complex may assist in the movement of protein and lipid components back to the endoplasmic reticulum. Alternatively spliced transcript variants have been described.

Community Annotation of COPB1 Add / Edit COPB1: Annotations

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Figure notes


• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


Legend

COPB1 is highly significantly mutated in
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COPB1 is significantly mutated in
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COPB1 is near significance in
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Click on a tumor type to see its full list of significant genes.

Data details


Mutation list for COPB1