COL21A1 Back

collagen, type XXI, alpha 1

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NCBI Description of COL21A1

This gene encodes the alpha chain of type XXI collagen, a member of the FACIT collagen family (fibril-associated collagens with interrupted helices). Type XXI collagen is localized to tissues containing type I collagen so, like other members of this collagen family, it may serve to maintain the integrity of the extracellular matrix. An alternatively spliced transcript variant has been described, but its full-length nature has yet to be determined.

Community Annotation of COL21A1 Add / Edit COL21A1: Annotations

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Figure notes

• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


COL21A1 is highly significantly mutated in
COL21A1 is significantly mutated in
COL21A1 is near significance in

Click on a tumor type to see its full list of significant genes.

Data details

Mutation list for COL21A1