COL16A1 Back

collagen, type XVI, alpha 1

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NCBI Description of COL16A1
This gene encodes the alpha chain of type XVI collagen, a member of the FACIT collagen family (fibril-associated collagens with interrupted helices). Members of this collagen family are found in association with fibril-forming collagens such as type I and II, and serve to maintain the integrity of the extracellular matrix. High levels of type XVI collagen have been found in fibroblasts and keratinocytes, and in smooth muscle and amnion.

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Figure notes


• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


Legend

COL16A1 is highly significantly mutated in
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COL16A1 is significantly mutated in
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COL16A1 is near significance in
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Click on a tumor type to see its full list of significant genes.

Data details


• Mutation list for COL16A1