COG5 Back

component of oligomeric golgi complex 5

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NCBI Description of COG5
The protein encoded by this gene is one of eight proteins (Cog1-8) which form a Golgi-localized complex (COG) required for normal Golgi morphology and function. The encoded protein is organized with conserved oligomeric Golgi complex components 6, 7 and 8 into a sub-complex referred to as lobe B. Alternative splicing results in multiple transcript variants. Mutations in this gene result in congenital disorder of glycosylation type 2I.

Community Annotation of COG5 Add / Edit COG5: Annotations

No community annotations yet for COG5.
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Figure notes


• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


Legend

COG5 is highly significantly mutated in
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COG5 is significantly mutated in
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COG5 is near significance in
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Click on a tumor type to see its full list of significant genes.

Data details


• Mutation list for COG5