CNST Back

consortin, connexin sorting protein

External References:      Wikipedia GeneCards HUGO COSMIC Google Scholar

NCBI Description of CNST
Targeting of numerous transmembrane proteins to the cell surface is thought to depend on their recognition by cargo receptors that interact with the adaptor machinery for anterograde traffic at the distal end of the Golgi complex. Consortin (CNST) is an integral membrane protein that acts as a binding partner of connexins, the building blocks of gap junctions, and acts as a trans-Golgi network (TGN) receptor involved in connexin targeting to the plasma membrane and recycling from the cell surface (del Castillo et al., 2010 [PubMed 19864490]).[supplied by OMIM, Jun 2010].

Community Annotation of CNST Add / Edit CNST: Annotations

No community annotations yet for CNST.
Sort mutations by: Tumor type  Mutation type  Position  
Straightedge cursor Expand

Figure notes


• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


Legend

CNST is highly significantly mutated in
(none)
CNST is significantly mutated in
(none)
CNST is near significance in
(none)

Click on a tumor type to see its full list of significant genes.

Data details


• Mutation list for CNST