CNOT4 Back

CCR4-NOT transcription complex, subunit 4

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NCBI Description of CNOT4

The protein encoded by this gene is a subunit of the CCR4-NOT complex, a global transcriptional regulator. The encoded protein interacts with CNOT1 and has E3 ubiquitin ligase activity. Several transcript variants encoding different isoforms have been found for this gene.

Community Annotation of CNOT4 Add / Edit CNOT4: Annotations

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Figure notes

• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


CNOT4 is highly significantly mutated in
CNOT4 is significantly mutated in
CNOT4 is near significance in

Click on a tumor type to see its full list of significant genes.

Data details

Mutation list for CNOT4