CNGB3 Back

cyclic nucleotide gated channel beta 3

External References:      Wikipedia GeneCards HUGO COSMIC Google Scholar

NCBI Description of CNGB3

This gene encodes the beta subunit of a cyclic nucleotide-gated ion channel. The encoded beta subunit appears to play a role in modulation of channel function in cone photoreceptors. This heterotetrameric channel is necessary for sensory transduction, and mutations in this gene have been associated with achromatopsia 3, progressive cone dystrophy, and juvenile macular degeneration, also known as Stargardt Disease.

Community Annotation of CNGB3 Add / Edit CNGB3: Annotations

No community annotations yet for CNGB3.
Sort mutations by: Tumor type  Mutation type  Position  
Straightedge cursor Expand

Figure notes

• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


CNGB3 is highly significantly mutated in
CNGB3 is significantly mutated in
CNGB3 is near significance in

Click on a tumor type to see its full list of significant genes.

Data details

Mutation list for CNGB3