CLOCK Back

clock homolog (mouse)

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NCBI Description of CLOCK
This gene product regulates circadian rhythm and metabolism. The protein encodes a transcription factor of the basic helix-loop-helix (bHLH) family and a DNA binding histone acetyltransferase. Polymorphisms in this gene may be associated with behavioral changes in certain populations and with obesity and metabolic syndrome. Alternative splicing results in multiple transcript variants.

Community Annotation of CLOCK Add / Edit CLOCK: Annotations

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Figure notes


• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


Legend

CLOCK is highly significantly mutated in
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CLOCK is significantly mutated in
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CLOCK is near significance in
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Click on a tumor type to see its full list of significant genes.

Data details


• Mutation list for CLOCK