CLIP3 Back

CAP-GLY domain containing linker protein 3

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NCBI Description of CLIP3
This gene encodes a member of the cytoplasmic linker protein 170 family. Members of this protein family contain a cytoskeleton-associated protein glycine-rich domain and mediate the interaction of microtubules with cellular organelles. The encoded protein plays a role in T cell apoptosis by facilitating the association of tubulin and the lipid raft ganglioside GD3. The encoded protein also functions as a scaffold protein mediating membrane localization of phosphorylated protein kinase B. Alternatively spliced transcript variants have been observed for this gene.

Community Annotation of CLIP3 Add / Edit CLIP3: Annotations

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Figure notes


• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


Legend

CLIP3 is highly significantly mutated in
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CLIP3 is significantly mutated in
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CLIP3 is near significance in
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Click on a tumor type to see its full list of significant genes.

Data details


• Mutation list for CLIP3