clathrin interactor 1

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NCBI Description of CLINT1

This gene encodes a protein with similarity to the epsin family of endocytic adapter proteins. The encoded protein interacts with clathrin, the adapter protein AP-1 and phosphoinositides. This protein may be involved in the formation of clathrin coated vesicles and trafficking between the trans-Golgi network and endosomes. Mutations in this gene are associated with a susceptibility to schizophrenia and psychotic disorders. Alternate splicing results in multiple transcript variants.

Community Annotation of CLINT1 Add / Edit CLINT1: Annotations

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Figure notes

• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


CLINT1 is highly significantly mutated in
CLINT1 is significantly mutated in
CLINT1 is near significance in

Click on a tumor type to see its full list of significant genes.

Data details

Mutation list for CLINT1