CLIC5 Back

chloride intracellular channel 5

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NCBI Description of CLIC5
This gene encodes a member of the chloride intracellular channel (CLIC) family of chloride ion channels. The encoded protein associates with actin-based cytoskeletal structures and may play a role in multiple processes including hair cell stereocilia formation, myoblast proliferation and glomerular podocyte and endothelial cell maintenance. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.

Community Annotation of CLIC5 Add / Edit CLIC5: Annotations

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Figure notes


• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


Legend

CLIC5 is highly significantly mutated in
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CLIC5 is significantly mutated in
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CLIC5 is near significance in
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Click on a tumor type to see its full list of significant genes.

Data details


• Mutation list for CLIC5