CLEC2B Back

C-type lectin domain family 2, member B

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NCBI Description of CLEC2B
This gene encodes a member of the C-type lectin/C-type lectin-like domain (CTL/CTLD) superfamily. Members of this family share a common protein fold and have diverse functions, such as cell adhesion, cell-cell signalling, glycoprotein turnover, and roles in inflammation and immune response. The encoded type 2 transmembrane protein may function as a cell activation antigen. An alternative splice variant has been described but its full-length sequence has not been determined. This gene is closely linked to other CTL/CTLD superfamily members on chromosome 12p13 in the natural killer gene complex region.

Community Annotation of CLEC2B Add / Edit CLEC2B: Annotations

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Figure notes


• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


Legend

CLEC2B is highly significantly mutated in
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CLEC2B is significantly mutated in
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CLEC2B is near significance in
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Click on a tumor type to see its full list of significant genes.

Data details


• Mutation list for CLEC2B