CLCA4 Back

chloride channel, calcium activated, family member 4

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NCBI Description of CLCA4

The protein encoded by this gene belongs to the calcium sensitive chloride conductance protein family. To date, all members of this gene family map to the same site on chromosome 1p31-p22 and share high degrees of homology in size, sequence and predicted structure, but differ significantly in their tissue distributions. Alternative splicing results in multiple transcript variants, only one of which is thought to be protein coding.

Community Annotation of CLCA4 Add / Edit CLCA4: Annotations

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Figure notes


• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


Legend

CLCA4 is highly significantly mutated in
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CLCA4 is significantly mutated in
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CLCA4 is near significance in
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Click on a tumor type to see its full list of significant genes.

Data details


Mutation list for CLCA4