cell death-inducing DFFA-like effector c

External References:      Wikipedia GeneCards HUGO COSMIC Google Scholar

NCBI Description of CIDEC

This gene encodes a member of the cell death-inducing DNA fragmentation factor-like effector family. Members of this family play important roles in apoptosis. The encoded protein promotes lipid droplet formation in adipocytes and may mediate adipocyte apoptosis. This gene is regulated by insulin and its expression is positively correlated with insulin sensitivity. Mutations in this gene may contribute to insulin resistant diabetes. A pseudogene of this gene is located on the short arm of chromosome 3. Alternatively spliced transcript variants that encode different isoforms have been observed for this gene.

Community Annotation of CIDEC Add / Edit CIDEC: Annotations

No community annotations yet for CIDEC.
Sort mutations by: Tumor type  Mutation type  Position  
Straightedge cursor Expand

Figure notes

• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


CIDEC is highly significantly mutated in
CIDEC is significantly mutated in
CIDEC is near significance in

Click on a tumor type to see its full list of significant genes.

Data details

Mutation list for CIDEC