CHST7 Back

carbohydrate (N-acetylglucosamine 6-O) sulfotransferase 7

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NCBI Description of CHST7
This gene belongs to the sulfotransferase gene family. Sulfotransferases generate sulfated glycosaminoglycan (GAG) moities during chondroitin sulfate biosynthesis. They create considerable structural diversity among chondroitin sulfates by transferring sulfate with remarkable specificity for the underlying oligosaccharide substrate. This gene product mainly transfers sulfate to N-acetylgalactosamine. The regulated expression of each member of this gene family may be an important determinant of sulfated GAGs expression and the associated function of chondroitin sulfates as regulators of many biologic processes. This gene is part of a gene cluster on chromosome Xp11.23.

Community Annotation of CHST7 Add / Edit CHST7: Annotations

No community annotations yet for CHST7.
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Figure notes


• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


Legend

CHST7 is highly significantly mutated in
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CHST7 is significantly mutated in
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CHST7 is near significance in
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Click on a tumor type to see its full list of significant genes.

Data details


• Mutation list for CHST7