CHST4 Back

carbohydrate (N-acetylglucosamine 6-O) sulfotransferase 4

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NCBI Description of CHST4
This gene encodes an N-acetylglucosamine 6-O sulfotransferase. The encoded enzyme transfers sulfate from 3'phosphoadenosine 5'phospho-sulfate to the 6-hydroxyl group of N-acetylglucosamine on glycoproteins. This protein is localized to the Golgi and is involved in the modification of glycan structures on ligands of the lymphocyte homing receptor L-selectin. Alternate splicing in the 5' UTR results in multiple transcript variants that encode the same protein.

Community Annotation of CHST4 Add / Edit CHST4: Annotations

No community annotations yet for CHST4.
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Figure notes


• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


Legend

CHST4 is highly significantly mutated in
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CHST4 is significantly mutated in
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CHST4 is near significance in
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Click on a tumor type to see its full list of significant genes.

Data details


• Mutation list for CHST4