CHST15 Back

carbohydrate (N-acetylgalactosamine 4-sulfate 6-O) sulfotransferase 15

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NCBI Description of CHST15

Chondroitin sulfate (CS) is a glycosaminoglycan which is an important structural component of the extracellular matrix and which links to proteins to form proteoglycans. Chondroitin sulfate E (CS-E) is an isomer of chondroitin sulfate in which the C-4 and C-6 hydroxyl groups are sulfated. This gene encodes a type II transmembrane glycoprotein that acts as a sulfotransferase to transfer sulfate to the C-6 hydroxal group of chondroitin sulfate. This gene has also been identified as being co-expressed with RAG1 in B-cells and as potentially acting as a B-cell surface signaling receptor. Alternative splicing results in multiple transcript variants encoding distinct isoforms.

Community Annotation of CHST15 Add / Edit CHST15: Annotations

No community annotations yet for CHST15.
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Figure notes

• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


CHST15 is highly significantly mutated in
CHST15 is significantly mutated in
CHST15 is near significance in

Click on a tumor type to see its full list of significant genes.

Data details

Mutation list for CHST15