CHST12 Back

carbohydrate (chondroitin 4) sulfotransferase 12

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NCBI Description of CHST12

The protein encoded by this gene belongs to the sulfotransferase 2 family. It is localized to the golgi membrane, and catalyzes the transfer of sulfate to position 4 of the N-acetylgalactosamine (GalNAc) residue of chondroitin and desulfated dermatan sulfate. Chondroitin sulfate constitutes the predominant proteoglycan present in cartilage, and is distributed on the surfaces of many cells and extracellular matrices. Alternatively spliced transcript variants differing only in their 5' UTRs have been found for this gene.

Community Annotation of CHST12 Add / Edit CHST12: Annotations

No community annotations yet for CHST12.
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Figure notes

• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


CHST12 is highly significantly mutated in
CHST12 is significantly mutated in
CHST12 is near significance in

Click on a tumor type to see its full list of significant genes.

Data details

Mutation list for CHST12