CHST11 Back

carbohydrate (chondroitin 4) sulfotransferase 11

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NCBI Description of CHST11

The protein encoded by this gene belongs to the sulfotransferase 2 family. It is localized to the golgi membrane, and catalyzes the transfer of sulfate to position 4 of the N-acetylgalactosamine (GalNAc) residue of chondroitin. Chondroitin sulfate constitutes the predominant proteoglycan present in cartilage, and is distributed on the surfaces of many cells and extracellular matrices. A chromosomal translocation involving this gene and IgH, t(12;14)(q23;q32), has been reported in a patient with B-cell chronic lymphocytic leukemia. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

Community Annotation of CHST11 Add / Edit CHST11: Annotations

No community annotations yet for CHST11.
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Figure notes

• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


CHST11 is highly significantly mutated in
CHST11 is significantly mutated in
CHST11 is near significance in

Click on a tumor type to see its full list of significant genes.

Data details

Mutation list for CHST11