CHRNA5 Back

cholinergic receptor, nicotinic, alpha 5

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NCBI Description of CHRNA5
The protein encoded by this gene is a nicotinic acetylcholine receptor subunit and a member of a superfamily of ligand-gated ion channels that mediate fast signal transmission at synapses. These receptors are thought to be heteropentamers composed of separate but similar subunits. Defects in this gene have been linked to susceptibility to lung cancer type 2 (LNCR2).

Community Annotation of CHRNA5 Add / Edit CHRNA5: Annotations

No community annotations yet for CHRNA5.
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Figure notes


• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


Legend

CHRNA5 is highly significantly mutated in
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CHRNA5 is significantly mutated in
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CHRNA5 is near significance in
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Click on a tumor type to see its full list of significant genes.

Data details


• Mutation list for CHRNA5