cholinergic receptor, nicotinic, alpha 1 (muscle)

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NCBI Description of CHRNA1

The muscle acetylcholine receptor consiststs of 5 subunits of 4 different types: 2 alpha subunits and 1 each of the beta, gamma, and delta subunits. This gene encodes an alpha subunit that plays a role in acetlycholine binding/channel gating. Alternatively spliced transcript variants encoding different isoforms have been identified.

Community Annotation of CHRNA1 Add / Edit CHRNA1: Annotations

No community annotations yet for CHRNA1.
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Figure notes

• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


CHRNA1 is highly significantly mutated in
CHRNA1 is significantly mutated in
CHRNA1 is near significance in

Click on a tumor type to see its full list of significant genes.

Data details

Mutation list for CHRNA1