CHL1 Back

cell adhesion molecule with homology to L1CAM (close homolog of L1)

External References:      Wikipedia GeneCards HUGO COSMIC Google Scholar

NCBI Description of CHL1
The protein encoded by this gene is a member of the L1 gene family of neural cell adhesion molecules. It is a neural recognition molecule that may be involved in signal transduction pathways. The deletion of one copy of this gene may be responsible for mental defects in patients with 3p- syndrome. This protein may also play a role in the growth of certain cancers. Alternate splicing results in both coding and non-coding variants.

Community Annotation of CHL1 Add / Edit CHL1: Annotations

No community annotations yet for CHL1.
Sort mutations by: Tumor type  Mutation type  Position  
Straightedge cursor Expand

Figure notes


• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


Legend

CHL1 is highly significantly mutated in
(none)
CHL1 is significantly mutated in
(none)
CHL1 is near significance in
(none)

Click on a tumor type to see its full list of significant genes.

Data details


• Mutation list for CHL1