CHKA Back

choline kinase alpha

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NCBI Description of CHKA
The major pathway for the biosynthesis of phosphatidylcholine occurs via the CDP-choline pathway. The protein encoded by this gene is the initial enzyme in the sequence and may play a regulatory role. The encoded protein also catalyzes the phosphorylation of ethanolamine. Two transcript variants encoding different isoforms have been found for this gene.

Community Annotation of CHKA Add / Edit CHKA: Annotations

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Figure notes


• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


Legend

CHKA is highly significantly mutated in
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CHKA is significantly mutated in
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CHKA is near significance in
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Click on a tumor type to see its full list of significant genes.

Data details


• Mutation list for CHKA