CFD Back

complement factor D (adipsin)

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NCBI Description of CFD
The protein encoded by this gene is a member of the trypsin family of peptidases. The encoded protein is a component of the alternative complement pathway best known for its role in humoral suppression of infectious agents. This protein is also a serine protease that is secreted by adipocytes into the bloodstream. Finally, the encoded protein has a high level of expression in fat, suggesting a role for adipose tissue in immune system biology.

Community Annotation of CFD Add / Edit CFD: Annotations

No community annotations yet for CFD.
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Figure notes


• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


Legend

CFD is highly significantly mutated in
(none)
CFD is significantly mutated in
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CFD is near significance in
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Click on a tumor type to see its full list of significant genes.

Data details


• Mutation list for CFD