CETN2 Back

centrin, EF-hand protein, 2

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NCBI Description of CETN2

Caltractin belongs to a family of calcium-binding proteins and is a structural component of the centrosome. The high level of conservation from algae to humans and its association with the centrosome suggested that caltractin plays a fundamental role in the structure and function of the microtubule-organizing center, possibly required for the proper duplication and segregation of the centrosome.

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Figure notes


• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


Legend

CETN2 is highly significantly mutated in
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CETN2 is significantly mutated in
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CETN2 is near significance in
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Click on a tumor type to see its full list of significant genes.

Data details


Mutation list for CETN2