CETN1 Back

centrin, EF-hand protein, 1

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NCBI Description of CETN1

The protein encoded by this gene plays important roles in the determination of centrosome position and segregation, and in the process of microtubule severing. This encoded protein is localized to the centrosome of interphase cells, and redistributes to the region of the spindle poles during mitosis, reflecting the dynamic behavior of the centrosome during the cell cycle.

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Figure notes


• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


Legend

CETN1 is highly significantly mutated in
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CETN1 is significantly mutated in
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CETN1 is near significance in
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Click on a tumor type to see its full list of significant genes.

Data details


Mutation list for CETN1