centromere protein O

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NCBI Description of CENPO

This gene encodes a component of the interphase centromere complex. The encoded protein is localized to the centromere throughout the cell cycle and is required for bipolar spindle assembly, chromosome segregation and checkpoint signaling during mitosis. Alternatively spliced transcript variants encoding multiple protein isoforms have been observed for this gene.

Community Annotation of CENPO Add / Edit CENPO: Annotations

No community annotations yet for CENPO.
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Figure notes

• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


CENPO is highly significantly mutated in
CENPO is significantly mutated in
CENPO is near significance in

Click on a tumor type to see its full list of significant genes.

Data details

Mutation list for CENPO