CENPN Back

centromere protein N

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NCBI Description of CENPN
The protein encoded by this gene forms part of the nucleosome-associated complex and is important for kinetochore assembly. It is bound to kinetochores during S phase and G2 and recruits other proteins to the centromere. Pseudogenes of this gene are located on chromosome 2. Alternative splicing results in multiple transcript variants that encode different protein isoforms.

Community Annotation of CENPN Add / Edit CENPN: Annotations

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Figure notes


• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


Legend

CENPN is highly significantly mutated in
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CENPN is significantly mutated in
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CENPN is near significance in
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Click on a tumor type to see its full list of significant genes.

Data details


• Mutation list for CENPN