CELF6 Back

CUGBP, Elav-like family member 6

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NCBI Description of CELF6

Members of the CELF/BRUNOL protein family contain two N-terminal RNA recognition motif (RRM) domains, one C-terminal RRM domain, and a divergent segment of 160-230 aa between the second and third RRM domains. Members of this protein family regulate pre-mRNA alternative splicing and may also be involved in mRNA editing, and translation. Multiple alternatively spliced transcript variants encoding different isoforms have been identified in this gene.

Community Annotation of CELF6 Add / Edit CELF6: Annotations

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Figure notes


• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


Legend

CELF6 is highly significantly mutated in
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CELF6 is significantly mutated in
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CELF6 is near significance in
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Click on a tumor type to see its full list of significant genes.

Data details


Mutation list for CELF6