CELF2 Back

CUGBP, Elav-like family member 2

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NCBI Description of CELF2
Members of the CELF/BRUNOL protein family contain two N-terminal RNA recognition motif (RRM) domains, one C-terminal RRM domain, and a divergent segment of 160-230 aa between the second and third RRM domains. Members of this protein family regulate pre-mRNA alternative splicing and may also be involved in mRNA editing, and translation. Alternative splicing results in multiple transcript variants encoding different isoforms.

Community Annotation of CELF2 Add / Edit CELF2: Annotations

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Figure notes


• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


Legend

CELF2 is highly significantly mutated in
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CELF2 is significantly mutated in
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CELF2 is near significance in
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Click on a tumor type to see its full list of significant genes.

Data details


• Mutation list for CELF2